Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis

University of California Irvine (UCI)

Status: Enrolling

Conditions: Gastrointestinal Peritoneal Carcinomatosis; Peritoneal Carcinomatosis

Treatments: Other: Biospecimen Collection (Blood, Ascites/Peritoneal Wash Fluid and/or Tumor Samples)

Study type: Interventional

Funder types: Other

Identifiers

NCT05844865

UCI 22-92 (Other Identifier)

2214

Details and patient eligibility

About

This is a pilot study gathering and using samples and data from patients with gastrointestinal peritoneal carcinomatosis. Participants will be asked for permission to provide blood and ascites/peritoneal wash fluid, tumor samples during their planned surgical procedure.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients must have a GI tumor
• Must have planned standard of care surgical procedure
• Age ≥ 18 years.
• Ability to understand and the willingness to sign a written informed consent

Exclusion criteria

• Pattens who are unable to comply with the study protocol

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Subjects with Gastrointestinal Primary Tumor with or without Peritoneal Carcinomatosis

Other group

Description:

Subjects with gastrointestinal (GI) primary tumor with or without peritoneal carcinomatosis who are undergoing planned standard of care (SOC) surgical procedures. Biospecimens such as blood, peritoneal wash fluid and tumor samples will be obtained.

Treatment:

Other: Biospecimen Collection (Blood, Ascites/Peritoneal Wash Fluid and/or Tumor Samples)