Patient Journey With Advanced Lung Cancer Positive for ALK Fusion in Brazil

Latin American Cooperative Oncology Group (LACOG)

Status: Completed

Conditions: Carcinoma, Non-Small-Cell Lung

Study type: Observational

Funder types: Other

Identifiers

NCT04947683

LACOG 1918

Details and patient eligibility

About

Observational, retrospective cohort study that will include patients diagnosed with NSCLC and ALK rearrangement between January 2015 and December 2020.

Enrollment: 101 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients older than 18 years;
• Newly diagnosed advanced stage IIIB-IV NSCLC (AJCC 8th edition) or locally advance/distant relapse in the period of January 2015 to December 2020.
• NSCLC with pathological confirmation of ALK rearrangement by immunohistochemistry, fluorescent in situ hybridization (FISH) or next generation sequencing (NGS);
• ECOG 0-4;
• Patients with CNS metastases are also considered eligible, regardless of the initial treatment instituted.

Exclusion criteria

• Incomplete medical chart in terms of date of diagnosis, ALK test results and outcomes