Patient-Reported Outcome Questionnaire for Systemic Mastocytosis

Adelphi Values

Status

Completed

Conditions

Aggressive Systemic Mastocytosis (ASM)

Smoldering Systemic Mastocytosis (SSM)

Mast Cell Leukemia (MCL)

SM w Assoc Clonal Hema Non-mast Cell Lineage Disease (SM-AHNMD)

Indolent Systemic Mastocytosis (ISM) ISM Subgroup Fully Recruited

Treatments

Other: Interview

Study type

Observational

Funder types

Industry

Identifiers

NCT02380222

BL7064A

Details and patient eligibility

About

The purpose of this study is to explore the key symptoms of individuals with systemic mastocytosis. Interviews of enrolled individuals will be conducted to learn about the disease symptoms and condition. The interview will last approximately 60 minutes and will be conducted by a trained interviewer, be audio-recorded (with patient consent), and all information provided by the patient will be treated confidentially and made anonymous so that it is non-identifiable. The interview may be conducted face-to-face, over the phone, or virtually via Skype, a free video conferencing program, depending upon the patient's geographic location. Patients will be compensated for their participating time.

This is not a medication-related study, and no medication will be distributed or tested during this study. Participation in this study will not affect any treatment or assistance that a patient currently receives or may receive in the future.

Enrollment

5 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Documented diagnosis of one of the following conditions based upon World Health Organization (WHO) diagnostic criteria: aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated clonal hematologic non-mast cell lineage disease (SM-AHNMD), mast cell leukemia (MCL), smoldering systemic mastocytosis (SSM), indolent systemic mastocytosis (ISM)
Diagnosis confirmed by bone marrow biopsy
Fluency in English
Willingness and ability to participate in a one-hour interview

Exclusion criteria

A condition or situation that would interfere with participation in an interview (e.g., cognitive impairment or disorder, alcohol or drug abuse)
Known human immunodeficiency virus or acquired immunodeficiency syndrome-related illness
Any other prior malignancy except for the following: Adequately treated basal cell or squamous cell skin cancer; In situ cervical cancer; Adequately treated Stage I or II cancer from which the subject is currently in complete remission, or other cancer from which the subject has been disease-free for 2 years