Patient Reported Symptom Control With THC or CBD Use

M.D. Anderson Cancer Center

Status: Active, not recruiting

Conditions: Hematopoietic and Lymphoid Cell Neoplasm; Cancer-Associated Pain; Malignant Solid Neoplasm

Treatments: Other: Electronic Health Record Review; Other: Questionnaire Administration

Study type: Observational

Funder types: Other

Identifiers

NCT04875286

NCI-2021-02853 (Registry Identifier)

2019-0753 (Other Identifier)

Details and patient eligibility

About

This study compares patients' attitudes regarding marijuana products for medical use and other treatments for cancer-related pain. This study may help researchers gain better understanding of patient's perception on their use of marijuana products in treating cancer-related pain and other common cancer-related symptoms.

Full description

PRIMARY OBJECTIVE:

I. To determine the patient's reported preference for cancer pain improvement with opioids, opioids with delta-9-tetrahydrocannabinol (THC)-marijuana and/or opioids with cannabidiol (CBD).

SECONDARY OBJECTIVES:

I. To determine the association between perception of cancer-related symptom relief and use of THC-marijuana and/or CBD.

II. To compare patient perception of THC-marijuana and/or CBD versus (vs.) cancer treatments in treatment of cancer.

III. To evaluate patient report of adverse effects experienced while using THC-marijuana and/or CBD.

IV. To evaluate patient reported concerns while using THC-marijuana and/or CBD. V. To evaluate patient attitude of dosing, forms and use of THC-marijuana and/or CBD.

VI. To evaluate demographic, physical and psychosocial factors that influence patient perception and attitudes of THC-marijuana and/or CBD.

VII. To explore the difference of patient perception of THC-marijuana and CBD in cancer centers in a legalized vs. a non-legalized state.

VIII. To explore the patient reported preference of THC-marijuana and CBD for cancer pain and symptom relief of patients in a Supportive Care Center vs. Integrative Medicine Center at University of Texas (U.T.) MD Anderson.

OUTLINE:

Patients' medical records are reviewed and then complete questionnaires over 27 minutes.

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients (inpatient or outpatient) seen by the Palliative Care and Integrative Medicine teams at The University of Texas MD Anderson Cancer Center (Texas) and the Palliative Care team at Banner MD Anderson Cancer Center (Arizona)
• Patients must be primary residents of Texas or Arizona
• Patients able to speak and read English
• Patients are 18 years old and above
• Patients should have a cancer diagnosis, cancer-associated pain, and taking strong opioids (morphine, oxycodone, hydrocodone, hydromorphone, oxymorphone, methadone, fentanyl)
• Patients who have used in the past 3 months or are using alternative botanical pain management while under prescription opioids

Exclusion criteria

• Patients who are not able to speak or read English
• Altered mental status as determined by the interviewer based on the ability to understand the nature of the study and consent process
• Patients who have not used medical marijuana and/or CBD products
• Patients who do not have cancer
• Patients who do not have cancer-associated pain
• Patients who are not taking opioids

Trial design

200 participants in 1 patient group

Observational (medical record review, questionnaires))

Description:

Patients' medical records are reviewed and then complete questionnaires over 27 minutes.

Treatment:

Other: Questionnaire Administration

Other: Electronic Health Record Review