Patient-ventilator Asynchrony During Noninvasive Ventilation Assessed Using Diaphragm Ultrasonography (ADULT)

Centre Hospitalier Saint Joseph Saint Luc de Lyon

Status: Unknown

Conditions: Diaphragm; Ultrasonography

Treatments: Other: Creation and detection of patient-respirator asynchronies

Study type: Interventional

Funder types: Other

Identifiers

NCT03114384

2017-A00346-47

Details and patient eligibility

About

Fifteen healthy subjects under non-invasive ventilation will be have a recording of surface electromyogram, measurements of airway flows and pressures as well as a continuous ultrasound. The provocation of leaks on the Ventilation circuit and expiratory trigger modulation will generate a number of asynchronies between the subject and the respirator.

These records will help to assess the agreement between the detection of asynchronies using electromyography of the respiratory muscles (technique of reference) and the diaphragmatic echography. We will also compare the respective performance of two techniques of diaphragmatic exploration (excursion and thickening of the diaphragm). A sensitivity of Ultrasound technique of at least 90% will be interpreted as a satisfactory index of concordance.

Enrollment: 15 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteer (male or female)
• Free and Informed Consent

Exclusion criteria

• Known pregnancy, parturient or nursing mother
• Minor under 18 years of age
• Major incapable
• Non-affiliation to the social security scheme
• Any history of respiratory pathology

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Healthy volunteers

Experimental group

Treatment:

Other: Creation and detection of patient-respirator asynchronies