Patients With Asymptomatic Hyperuricemia Have Stronger Local Inflammatory Response and Worse Outcome After Total Knee Arthroplasty

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Zhejiang University

Status

Not yet enrolling

Conditions

Arthritis Knee

Study type

Observational

Funder types

Other

Identifiers

NCT05476367
2021-0785

Details and patient eligibility

About

We identify all patients who had undergone primary total knee arthroplsty(TKA) from April 1, 2015, to March 30, 2016. Patients are grouped by uric acid level. The knee society score(KSS score) and the hospital for special surgery knee score (HSS score) before the surgery and 6 years after the surgery will be collected. Also the clinical data will be collected.

Enrollment

614 estimated patients

Sex

All

Ages

18 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

patients who had undergone primary TKA from April 1, 2015, to March 30, 2016

Exclusion criteria

(1) infection, (2) rheumatoid arthritis, (3) ankylosing spondylitis, (4) revision surgery, (5) patients with unicondylar knee replacement, (6) patients who have been diagnosed with gout or previous gouty symptoms, and (7) patients combined with preoperative redness or swelling.

Trial design

614 participants in 2 patient groups

patients with normal uric acid level
Description:
The uric acid level is below 420 μmol/L in men and 360 μmol/L in women
patients with high uric acid level
Description:
The uric acid level is higher than 420 μmol/L in men and 360 μmol/L in women.

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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