PBMT on Muscular Performance and Recovery in Different Time-points

University of Nove de Julho

Status: Completed

Conditions: Phototherapy

Treatments: Device: Photobiomodulation Therapy (PBMT)

Study type: Interventional

Funder types: Other

Identifiers

NCT03420391

113553

Details and patient eligibility

About

Recent studies with photobiomodulation therapy (PBMT) have shown positive results delaying skeletal muscle fatigue and improving the status of biochemical markers related to skeletal muscle damage when these therapies were applied before exercise. The aim of this project is to verify the effects of PBMT in improvement of skeletal muscle performance and skeletal muscle recovery in healthy male subjects. This project aim also to validate the concept that simultaneous use of three wavelengths and light sources lead to optimized action independently of time-window between irradiation and the exercise.

Full description

This is a randomized, triple-blinded, placebo-controlled trial. Sixty healthy untrained male subjects will be randomly allocated to six experimental groups: Placebo, Control, PBMT 5 mins, PBMT 3h, PBMT 6h and PBMT 24 hours. PBMT will be applied precisely two minutes after baseline MVC test. Then, after five minutes, 3, 6 hours or 1 day (24 hours) of PBMT the eccentric exercise protocol will be performed. We will analyze maximum voluntary contraction (MVC), creatine kinase (CK) activity and delayed onset muscle soreness (DOMS). Assessments will be performed at baseline, immediately after (1 minute), 1 hour, 24 and 48 hours after the eccentric exercise protocol.

Enrollment: 60 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• not athletes or who engage in physical activity at most once a week
• Individuals should not present a history of musculoskeletal injury in the hip and knee regions in the two months prior to the studies
• they should not be using pharmacological agents and / or nutritional supplements
• They must attend 100% of the data collections.

Exclusion criteria

• Individuals who do not meet the criteria mentioned above or who present musculoskeletal damage during collection were excluded from the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 6 patient groups, including a placebo group

Placebo PBMT

Placebo Comparator group

Description:

Participants will be treated with placebo PBMT in different time-points before the eccentric exercise protocol (5 minutes, 3 hours, 6 hours or 24 hours). Assessments will be performed at baseline, 1 minute, 1 hour, 24 and 48 hours after the end of exercise protocol.

Treatment:

Device: Photobiomodulation Therapy (PBMT)

5 Minutes

Active Comparator group

Description:

Participants will be performed the eccentric exercise protocol 5 minutes after PBMT. Assessments will be performed at baseline, 1 minute, 1 hour, 24 and 48 hours after the end of exercise protocol.

Treatment:

Device: Photobiomodulation Therapy (PBMT)

3 Hours

Active Comparator group

Description:

3 hours: Participants will be performed the eccentric exercise protocol 3 hours after PBMT. Assessments will be performed before at baseline, 1 minute, 1 hour and 24, 48 hours after the end of exercise protocol.

Treatment:

Device: Photobiomodulation Therapy (PBMT)

6 Hours

Active Comparator group

Description:

6 hours: Participants will be performed the eccentric exercise protocol 6 hours after PBMT. Assessments will be performed at baseline, 1 minute, 1 hour, 24 and 48 hours after the end of exercise protocol.

Treatment:

Device: Photobiomodulation Therapy (PBMT)

24 hours

Active Comparator group

Description:

24 hours: Participants will be performed the eccentric exercise protocol 24 hours after PBMT. Assessments will be performed before at baseline, 1 minute, 1 hour, 24 and 48 hours after the end of exercise protocol.

Treatment:

Device: Photobiomodulation Therapy (PBMT)

Control

No Intervention group

Description:

Participants will not receive intervention. Assessments will be performed at baseline, 1 minute, 1 hour, 24 and 48 hours after the end of exercise protocol.