PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes

Cairo University (CU)

Status: Enrolling

Conditions: Dry Eye; Polycystic Ovary Syndrome; Obesity

Treatments: Behavioral: exercise and limiting diet; Behavioral: diet limitation

Study type: Interventional

Funder types: Other

Identifiers

NCT07366944

IRB000-14233-63

Details and patient eligibility

About

Women with polycystic ovarian syndrome (PCOS) may complain dryness of their eyes especially obese ones. lifestye changes are main treatrment fro both problems

Full description

Forty females with PCOS, eye dryness , and obesity will asigned to group I or Group II, n=20 for each group. Both groups will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks.

Enrollment: 40 estimated patients

Sex: Female

Ages: 30 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• PCOS women
• obese class I
• bilateral dryness of eye

Exclusion criteria

• liver disoease
• cardiac disease
• renal disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

group number 1

Experimental group

Description:

twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks.

Treatment:

Behavioral: exercise and limiting diet

group number 2

Active Comparator group

Description:

Twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks.

Treatment:

Behavioral: diet limitation