PD-Improved Dialysis Efficiency With Adapted APD (PD-IDEA)

Fresenius Medical Care (FMC)

Status: Completed

Conditions: Chronic Renal Failure

Treatments: Other: Treatment with Adapted Automated Peritoneal Dialysis (aAPD)

Study type: Observational

Funder types: Industry

Identifiers

NCT02470598

PD-aAPD-01-INT

Details and patient eligibility

About

The aim of this study is to observe the effect of adapted APD (aAPD) on maintenance and/or improvement of the hydration status of more than 250 PD patients, and to observe the tolerability of the therapy over a long period.

Full description

In some studies it has been observed that the use of a combination of short dwell/small volume and long dwell/large volume can improve the effectiveness of APD. However, these studies have been performed in a small number of patients during a short observation period.

The aim of this study is to assess the hydration status of PD patients treated with aAPD and observe its development during one year using the BCM-Body Composition Monitor (BCM), a bioimpedance spectroscopy (BIS) device. In addition, it is intended to observe the variability of aAPD prescriptions and their influence on the hydration status of the patients.

This is a purely non-interventional, observational study, where treatment decisions are completely guided by the discretion of the attending nephrologists.

Enrollment: 182 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• CKD patients with indication for renal replacement therapy
• Patient treated or to be treated with aAPD
• Fluid status regularly monitored with BCM

Exclusion criteria

• Patients who have any condition prohibiting the use of BCM like patients with major amputations (e.g. lower leg)
• Participation in an interventional study which could have an effect on the study objectives hydration status and dialysis adequacy (e.g. studies on PD solutions, studies on diuretics)