PECBLOCK for the Treatment of Pain After Breast Surgery

Centre hospitalier de l'Université de Montréal (CHUM)

Status: Completed

Conditions: Cancer; Pain

Treatments: Procedure: PECBLOCK under echoguidance

Study type: Interventional

Funder types: Other

Identifiers

NCT01670448

CE12.231

Details and patient eligibility

About

Pain after breast cancer surgery could be severe and about 1/3 of patients will develop chronic pain. The PECBLOCK is the injection of local anesthetics between the two pectoral muscles to block pectoral nerves and intercostal nerves innervating the breast. The aim of this study is to evaluate the efficacy of the PECBLOCK performed under echoguidance in minor and major breast surgery. The prevention of chronic pain following surgery will also be evaluated.

Enrollment: 128 patients

Sex: Female

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• women aged 18-85 yrs old
• patients ASA status I-IV

Exclusion criteria

• refusal of the PECBLOCK
• allergy to a drug used in the protocol (local anesthetic)
• patients with chronic pain before the surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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128 participants in 2 patient groups, including a placebo group

PECBLOCK performed with bupivacaine

Active Comparator group

Description:

Active drug given through PECBLOCK in these patients.

Treatment:

Procedure: PECBLOCK under echoguidance

PECBLOCK performed with NaCl 0.9%

Placebo Comparator group

Description:

Placebo drug given through PECBLOCK in these patients

Treatment:

Procedure: PECBLOCK under echoguidance