Pecs Block vs Local Infiltration in Mastectomy (PBLIM)

Hasanuddin University

Status: Completed

Conditions: Pain, Postoperative

Treatments: Drug: LIA; Drug: PECS II block

Study type: Interventional

Funder types: Other

Identifiers

NCT06451705

173/UN4.6.4.5.31/PP36/2AZ4

Details and patient eligibility

About

Studied the comparison between PECS II block and LIA on pain intensity, opioid requirements, RNL, and postoperative IL-6 levels in MRM patients.

Enrollment: 30 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Age: 18-60 years old.
2. Body weight (BW): 50-70 kg.
3. Height (TB): 150-170 cm.
4. Body mass index (BMI): 18.5-29.9 kg/m2.
5. American Society of Anesthesiologists physical status (ASA PS) class I-II.
6. Patients undergoing elective MRM surgery under general anesthesia.

Exclusion criteria

1. Patients with contraindications to PECS II block.
2. Patients with contraindications to LIA.
3. Patients with coagulation disorders or receiving anticoagulant therapy.
4. Patients with a history of chronic pain.
5. Patients with a history of allergy to study materials.
6. Patients with a history of previous breast surgery.
7. Patient refuses to participate in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

PECS

Active Comparator group

Description:

PECS II block before surgery using isobaric bupivacaine 0.25% 20 mL (50 mg)

Treatment:

Drug: PECS II block

LIA

Active Comparator group

Description:

Local infiltration anesthesia after completion of surgery using isobaric bupivacaine 0.25% 20 mL (50 mg)

Treatment:

Drug: LIA