Pectin Supplemented Enteral Feedings in Critically Ill Patients

Zhejiang University

Status: Withdrawn

Conditions: Dietary Fiber; Enteral Nutrition

Treatments: Other: enteral nutrition feeding; Dietary Supplement: pectin-supplemented enteral nutrition feeding

Study type: Interventional

Funder types: Other

Identifiers

NCT04438473

2019-112

Details and patient eligibility

About

The current study will enroll critically ill patients who are going to require enteral nutrition support and randomize them to standard formula enteral nutrition or pectin-supplemented enteral nutrition in 7 days. The occurrence of enteral nutrition-related complications will be recorded and compared between groups.

The study is trying to assess whether the use of pectin will improve the enteral nutrition-related complications in critically ill patients.

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18-80 years old, with informed consent to participate;
• Critically ill patients who require enteral nutrition support

Exclusion criteria

• Patients with lung infection at admission
• Condition which contraindicates enteral feeding (i.e. intestinal obstruction)
• Lack of enteral access
• Any condition that would contraindicate use of the enteral nutrition
• Require enteral nutrition support for less than 1week or more than 4 weeks from enrollment

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 2 patient groups, including a placebo group

Pectin

Experimental group

Description:

sequential supplementation with combination of 90ml pectin and 500ml enteral nutrition formula for 7 days

Treatment:

Dietary Supplement: pectin-supplemented enteral nutrition feeding

Control

Placebo Comparator group

Description:

standard formula enteral nutrition feeding without pectin for 7 days

Treatment:

Other: enteral nutrition feeding