Pediatric Aggression and Violence

Cincinnati Children's Hospital Medical Center logo

Cincinnati Children's Hospital Medical Center

Status

Completed

Conditions

Pediatric Aggression and Violence

Study type

Observational

Funder types

Other

Identifiers

NCT01253343
2010-0892

Details and patient eligibility

About

Violence and aggression on pediatric psychiatry units has led to staff and patient injuries and even deaths around the country. In an effort to improve safety, the investigators have developed a method (with the Brief Rating of Child and Adolescent Aggression) of identifying children and adolescents at a higher risk for aggression and violence on the units. In order to improve this prediction, the investigators plan to study salivary hormones in low risk children and high risk children. The salivary hormones to be studied include cortisol, testosterone, and dehydroepiandrosterone sulfate (DHEAS). The investigators expect to improve the investigators current ability to predict the severity and type of pediatric aggression and violence on the inpatient units by combining information from the Brief Rating of Child and Adolescent Aggression (BRACHA), the Predatory-Affective Aggression Scale (Vitiello et al., 1990), and salivary hormones.

Enrollment

17 patients

Sex

Male

Ages

7 to 9 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Prepubescent males (per parent report), African American or Caucasian, between 7 and 9 years old
  2. Ability of the subject to provide assent
  3. Ability of the guardian to give parental permission
  4. Completion of the BRACHA questionnaire
  5. Completion of the Predatory-Affective Aggression Scale (PAAS)

Exclusion criteria

  1. Viral or bacterial infection or treatment with antibiotics within two weeks of screening
  2. Recent surgery (within 8 weeks of screening)
  3. Bleeding gums (within 8 weeks of screening)
  4. Currently detained in a juvenile detention
  5. Currently taking medications such as antipsychotic medications (besides Aripiprazole), steroids and beta adrenergic agonists that affect hormones
  6. If it is the investigator's clinical judgment that the subject should be excluded if it is in the subject's best interest or due to any other factor that may interfere with study results

Trial design

17 participants in 2 patient groups

inpatient high aggression
inpatient low aggression

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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