Pediatric Eye Care Investigated Team (PECT)

Sun Yat-sen University

Status: Unknown

Conditions: Children; Systemic Disease; Eye Diseases; Ocular Surface Disease

Study type: Observational

Funder types: Other

Identifiers

NCT05247099

2021KYPJ185

Details and patient eligibility

About

Use cohort research to analyze and compare eyes of healthy children and children with systemic diseases. Understand and analyze the incidence, characteristics and influencing factors of children's ocular surface diseases. Establish a multi-center children's eye data sharing platform to provide basic data support for the diagnosis and treatment of children's ocular surface diseases.

Full description

Use cohort research to analyze and compare eyes of healthy children and children with systemic diseases. Understand and analyze the incidence, characteristics and influencing factors of children's ocular surface diseases. Establish a multi-center children's eye data sharing platform to provide basic data support for the diagnosis and treatment of children's ocular surface diseases.

All participants will be recruited from Zhongshan Ophthalmic Center, Sun Yat-sen University and Affiliated Foshan Maternity & Child Healthcare Hospital, Southern Medical University. Only children with written informed consent from their parents can participate in this study.

Participants will be excluded for (1) age>18; (2) previous use of orthokeratology lenses or low-concentration atropine; (3) allergy to compound tropicamide eye drop; (4) any history of ocular surgery.

All participants will undergo optometry and biometric measurements by a trained team. The axial length (AL), central corneal thickness (CCT), anterior corneal radii of curvature, anterior chamber depth (ACD), lens thickness (LT), the curvature power of the central flat meridian (K1) and the central steep meridian (K2), the ocular surface and fundus will be measured. All measurements will be taken in room light condition (1000 lux).

Enrollment: 1,000 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1. Age≤18
• 2. Cooperate with eye examination
• 3. Sign informed consent

Exclusion criteria

• 1. Cannot cooperate with eye examination
• 2. The researcher believes that the patient is not suitable to participate in the study.

Trial design

1,000 participants in 2 patient groups

children with systemic diseases

Description:

Systemic diseases such as Nephritic syndrome, and other systemic diseases that can affect the eyes.

healthy children

Description:

The exclusion criteria for the subjects were eye diseases or other systemic diseases that can affect the quality or volume of tears or the secretion of tears. These included 1. eyelid diseases: eyelid entropion, eyelid ectropion, ptosis, and palpebral dyskinesia; 2. conjunctival diseases: pterygium and conjunctivitis; 3. history of ocular surface chemical injury; 4. history of eye surgery within 6 months or history of retinal laser photocoagulation; 5. systemic diseases: Sjogren syndrome, Parkinson's disease, rheumatoid arthritis, Grave's disease, systemic lupus erythematosus, and others.