Pediatric Hypertension Registry (PHREG)

Wake Forest University (WFU)

Status: Terminated

Conditions: Hypertension; Pediatric Disorder

Study type: Observational

Funder types: Other

Identifiers

NCT03305562

IRB00046001

Details and patient eligibility

About

Pediatric hypertension is increasingly common and is a precursor for adult cardiovascular and renal disease. But even during childhood, hypertension is associated with significant morbidity, including cognitive impairment and organ damage. However, the cause of pediatric hypertension, the response to treatment, and the mechanisms behind organ damage are incompletely understood. Due to these limitations, there are no first-line medications, and treatment is often inadequate. An improved comprehension of the course of pediatric hypertension could enhance clinical care. The goal of this proposal is to create a registry of patients with hypertension to better enable research into this important disease. This patient registry will enhance the investigators ability to quickly collect and analyze data for research studies.

Full description

The investigators will include all subjects evaluated at the Brenner Children's Hospital Pediatric Nephrology clinic since January 1st, 2013 with a diagnosis of high blood pressure confirmed with three separate blood pressure measurements >=90th percentile for age, sex, and height, or >120/80 mmHg. The investigators will exclude patients whose initial evaluation occurred on or after their 18th birthday.

Enrollment: 179 patients

Sex: All

Ages: Under 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients at one of the following : Wake Forest Baptist Health Brenner Children's Hospital Pediatric Nephrology clinic Emory University Pediatric Nephrology

• Diagnosis of hypertension confirmed with three separate blood pressure measurements
• Diagnosis after January 2013
• >90th percentile for age, sex, height, or >120/80.

Exclusion criteria

• Patients whose initial evaluation occurred on or after their 18th birthday.

Trial design

179 participants in 2 patient groups

Retrospective cohort

Description:

The cohort of patients seen prior to the implementation of a standardized clinical management protocol on 10/01/2017 whose data is collected retrospectively.

Prospective cohort

Description:

The cohort of patients seen initially seen after implementation of a standardized clinical management protocol on 10/01/2017 whose data is collected prospectively.