PEEP During Induction of Anesthesia in Small Children

Seoul National University

Status: Completed

Conditions: Pediatric Anesthesia

Treatments: Other: PEEP; Other: ZEEP

Study type: Interventional

Funder types: Other

Identifiers

NCT03540940

H 1804-100-938

Details and patient eligibility

About

Positive end-expiratory pressure (PEEP) applied during induction of anesthesia prevents atelectasis formation and increases the duration of nonhypoxic apnea in obese and nonobese patients. PEEP also prevents atelectasis formation in pediatric patients. Because pediatric patients arterial desaturation during induction of anesthesia develops rapidly, we studied the clinical benefit of PEEP applied during anesthesia induction.

Enrollment: 60 patients

Sex: All

Ages: 1 month to 2 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pediatric patients undergoing general anesthesia using endotracheal intubation

Exclusion criteria

• previous history of lung disease
• anticipated difficulty in airway management

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

zero positive end expiratory pressure

Experimental group

Treatment:

Other: ZEEP

Positive end expiratory pressure

Experimental group

Treatment:

Other: PEEP