PEEP Titration and Lung Recruitment Potential Assessed by 3D EIT

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Enrolling

Conditions: Respiratory Failure; ARDS

Treatments: Procedure: lung recruitment potential assessed by 3D EIT; Procedure: PEEP titration by 3D eit

Study type: Observational

Funder types: Other

Identifiers

NCT06594601

PEEP by 3D-EIT for ARDS

PUMCH

Details and patient eligibility

About

In a population of ARDS patients, we explore the influence of different PEEP levels on regional ventilation distribution, ventilation homogeneity, and the center of ventilation, optimal PEEP and lung recruitment potential as well as the extent of lung collapse and overdistension as detected by 3D-EIT.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients on mechanical ventilation.
• Diagnosis of ARDS was based on the Berlin definition
• lung recruitment potential assessment and PEEP titration was proper for the ARDS patients determined by the attending doctor

Exclusion criteria

• Under 18 years of age.
• Pregnant women;
• Ribcage malformation
• Any contraindication to the use of EIT (e.g. automatic implantable cardioverter defibrillator, and implantable pumps).
• Hemodynamic instability, unable to tolerate high PEEP;
• High-risk individuals with pneumothorax, mediastinal emphysema, etc.

Trial design

50 participants in 2 patient groups

lung recruitment potential assessed by 3D EIT in ARDS

Description:

Diagnosis of ARDS was based on the Berlin definition, who have receivied mechanical ventilation. The enrolled patients received a lung recruitment potential assessment by 3D EIT( as the follwoing mentioned )

Treatment:

Procedure: lung recruitment potential assessed by 3D EIT

PEEP titration by 3D EIT for ARDS

Description:

Diagnosis of ARDS was based on the Berlin definition, who have receivied mechanical ventilation. The enrolled patients received a lung PEEP tirtation by 3D EIT( as the follwoing mentioned )

Treatment:

Procedure: PEEP titration by 3D eit