Penetration and Compartimentation of HIV

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: HIV

Treatments: Other: sample

Study type: Observational

Funder types: Other

Identifiers

NCT02513758

0201078

DGS 2002/0521 (Other Identifier)

Details and patient eligibility

About

Genital mucosa is the main way of HIV penetration. Many cells can be involved (epithelial cells, Langerhans cells) and antibodies may also play a critical role. The investigators' study aims to precise the role of each type of cells, the interaction cell-cell and cell-antibodies.

Full description

At inclusion, men will have a two blood sampling tubes of 10 ml each, a saliva sample and a sample of sperm and women will have a two blood sampling tubes of 10 ml each, a saliva sample and a sampling cervicovaginal secretions

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults (> 18 year-old) HIV positive,
• HIV-CV> 1000 cp/ml,

Exclusion criteria

• children

Trial design

200 participants in 1 patient group

HIV patients

Description:

Men will have blood sampling tubes of 10 ml each, a saliva sample and a sample of sperm Women will have a two blood sampling tubes of 10 ml each, a saliva sample and a sampling cervicovaginal secretions

Treatment:

Other: sample