PENG Block vs Supra-inguinal Fascia Iliaca Compartment Block for Postoperative Opioids Consumption and Early Motor Recovery After THA: a Randomized Controlled Non-inferiority Clinical Trial.

University of Liege

Status and phase: Unknown; Phase 4

Conditions: Total Hip Arthroplasty

Treatments: Drug: Ropivacaine 0,75% in PENG block; Drug: Ropivacaine 0,375% in SFICB block; Procedure: Pericapsular nerves group (PENG) block; Procedure: Supra-inguinal fascia-iliaca compartment block

Study type: Interventional

Funder types: Other

Identifiers

NCT04690023

2020/381

Details and patient eligibility

About

To compare the impact of pericapsular nerve group block (PENG) versus the supra-inguinal fascia-iliaca compartment block (SFICB) in postoperative analgesia, opioid sparing and enhanced recovery after surgery of total hip arthroplasty by poster-lateral approach.

Full description

ASA physical status 1, 2 and 3 patients scheduled to undergo elective total hip arthroplasty by poster-lateral (Moore) surgical approach with spinal anesthesia.

The investigators want to confirm the non-inferiority of the SFICB compared to the PENG block on postoperative first 6 hours after surgery NRS pain score and 48 hours opioids consumption, and the difference between these in terms of early recovery and motor impact on two first day after surgery. The principal investigator perform these regional anesthesia techniques with ultrasound guided injections.

Enrollment: 82 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults patients scheduled to undergo elective primary total hip arthroplasty by posterior surgical approach with spinal anesthesia

Exclusion criteria

• Patient refusal
• Allergy to administrated drugs or local infection
• Pregnancy
• History of chronic pain
• Drugs addiction
• Mental ou neurological diseases
• Kidney or liver serious diseases

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

82 participants in 2 patient groups

PENG block

Active Comparator group

Description:

Patients scheduled for total hip arthroplasty with spinal anesthesia receive before intra-thecal injection, ultrasound-guided PENG block. Patients in PENG group receive multimodal postoperative analgesia techniques coupled with morphine PCA pump.

Treatment:

Drug: Ropivacaine 0,75% in PENG block

Procedure: Pericapsular nerves group (PENG) block

SFICB block

Active Comparator group

Description:

Patients scheduled for total hip arthroplasty with spinal anesthesia receive before intra-thecal injection, ultrasound-guided supra-inguinal fascia iliaca compartment block. Patients in SFICB group receive multimodal postoperative analgesia techniques coupled with morphine PCA pump.

Treatment:

Drug: Ropivacaine 0,375% in SFICB block

Procedure: Supra-inguinal fascia-iliaca compartment block