PENS or TENS for Pain in Pancreatic Cancer

Fuda Cancer Hospital, Guangzhou

Status: Completed

Conditions: Cancer Pain; Pain; Pancreatic Cancer

Treatments: Device: PENS; Device: TENS

Study type: Interventional

Funder types: Other

Identifiers

NCT03331055

2017-TCM-01

Details and patient eligibility

About

This study evaluates the effect of percutaneous electrical nerve stimulation (PENS) and transcutaneous nerve stimulation (TENS) for pain relieving in patients with pancreatic cancer. Patients will randomly allocated into PENS group, Tens group and control group.

Full description

PENS and TENS have been reported with analgesic effect in patients with pain, including cancer pain, lower back pain, neck pain, stomachache and so on.

Effect and mechanism of PENS on pain relieving has been widely researched. With additional electrical stimulation in certain frequency and intensity to conventional acupuncture, pain controlling effect has been largely enhanced. However, invasive operation limits its application and acceptability, especially on pancreatic cancer.

TENS is an advanced technique generated from PENS, which is much more welcome for its noninvasive character. Further more, its analgesic effect on cancer pain has been proved by several multi-central, randomized, clinical trials.

Enrollment: 36 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pancreatic cancer with pain;
• Haven't underwent neurolytic celiac plexus block in the past 1 month;
• With anticipatory survival of more than 3 months.

Exclusion criteria

• Metastatic pancreatic cancer;
• Can not tolerate 30 min of lieing in prostrate or side position;
• PS>3;
• Who has been recruited in other clinical trial for pain releiving;
• Who underwent radiotherapy or local radiactive seeds implantation for pain releiving in the past month;
• Imaging diagnosed with encephalic tumor or metastasis;
• Who with cardiac pacemaker or metal stand;

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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36 participants in 3 patient groups

percutaneous stimulation

Experimental group

Description:

PENS in 2/100HZ, 30 min for each time, twice a day, for 3 days. With conventional analgesic medication if necessary.

Treatment:

Device: PENS

trancutaneous stimulation

Experimental group

Description:

TENS in 2/100HZ, 30 min for each time, twice a day, for 3 days. With conventional analgesic medication if necessary.

Treatment:

Device: TENS

Control

No Intervention group

Description:

Conventional analgesic medication is offered.