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Pentacam Study of the Cornea in RA Patients

M

Minia University

Status

Unknown

Conditions

RA - Rheumatoid Arthritis

Treatments

Diagnostic Test: Pentacam

Study type

Observational

Funder types

Other

Identifiers

NCT05241639
632-6/2020.

Details and patient eligibility

About

To evaluate the effect of rheumatoid arthritis (RA) activity on the corneal densitometry, corneal curvature (CC), central corneal thickness (CCT), and lens densitometry by Pentacam and compared these parameters with those of age-matched healthy control subjects

Full description

Case - control observational study on RA patients which divided into 2 groups, each group 120 eyes of 60 patients, group 1 of RA in the remission state and group 2 of RA in the active state. Group 3 of 120 eyes of healthy controls. Pentacam was used to measure corneal densitometry, CC, CCT, and lens densitometry. The cornea was divided into 4 concentric zones (0-2, 2-6, 6-10, and 10-12) and anterior, central, and posterior layers according to the depth

Enrollment

60 estimated patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • The included patients had aged more than 20 years with RA only without ocular manifestations with clinically clear cornea with normal anterior and posterior segment examinations with normal intraocular pressure (IOP)

Exclusion criteria

  • We excluded patients with ocular problems as corneal opacity, cataract, glaucoma, errors of refraction, topical application of eye drops except for topical artificial tears. The presence of systemic diseases other than RA as DM, hypertension were also excluded

Trial design

60 participants in 3 patient groups

group 1
Description:
of RA in the remission state
Treatment:
Diagnostic Test: Pentacam
group 2
Description:
of RA in the active state
Treatment:
Diagnostic Test: Pentacam
Group 3
Description:
120 eyes of healthy controls.
Treatment:
Diagnostic Test: Pentacam

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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