Pentraxin-3 in Hysterectomy Patients

Muğla Sıtkı Koçman University

Status

Completed

Conditions

Laparoscopic Hysterectomy

Abdominal Hysterectomy

Treatments

Diagnostic Test: PTX-3

Study type

Observational

Funder types

Other

Identifiers

NCT04366375

19.03.15-58-56

Details and patient eligibility

About

Comparison of the Tissue Trauma Markers Following Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy

Full description

Acute trauma and major surgeries activate a series of cascades to evoke systemic inflammatory response. The magnitude of the resulting inflammatory response is proportional to the severity of the tissue trauma. Abdominal or laparoscopic technique is widely used for the purpose of hysterectomy surgery. It is crucial for many aspects to compare these two techniques of hysterectomy in terms of the surgery-induced trauma.

In this study, the severity of the inflammatory response resulting from the tissue trauma due to the techniques of TLH+BSO and TAH+BSO applied in our department were compared based on the PTX-3 molecule.

Enrollment

40 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

·TLH+BSO patients and TAH+BSO patients

Exclusion criteria

History of a chronic disease (coronary artery disease, diabetes mellitus, hypertension, coronary liver failures, chronic kidney disease, chronic respiratory diseases, connective tissue disorders) which may affect levels of PTX-3 and other inflammatory markers.
Prior surgery due to malignancy.
History of an intra-abdominal surgery, except for cesarean section.
History of any disease which may lead to intra-abdominal adhesions (endometriosis, past pelvic infection).