Peppermint Aroma and Physiological Parameters

Alexandria University

Status: Completed

Conditions: Mechanical Ventilation Complication

Treatments: Other: Placebo; Other: Aromatherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05541809

1532020

Details and patient eligibility

About

Three drops of peppermint oil will be dropped on a cotton ball that will be fixed in the patient's collar. In the placebo group, peppermint oil will be replaced with water.

Full description

Mechanical ventilathetion increases the anxiety of critically ill patients. The physiological parameters of those patients are affected by stress. Peppermint inhalation reduces stress and improves physiological parameters in many studies, but none of these studies used peppermint inhalation on mechanically ventilated patients.

Patients who are conscious on mechanical ventilation via endotracheal via tube will be randomly assigned to two groups. Patients will be kept intubated and mechanically ventilated. Nothing will be changed in patients' mechanical ventilation data. The intervention group will receive peppermint inhalation intervention, and the placebo group received water inhalation intervention. Patients in both groups will be assessed for their smell ability by Sniffin Sticks-test before starting the interventions.

Three drops of undiluted peppermint oil will be dropped on a cotton ball. Then it will be placed about 20 cm from the patient's nose. It will be fixed on the patient's collar. In the placebo group, the cotton ball will be soaked in water. Then, patients will be monitored for one hour.

Enrollment: 106 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Patients with

• (1) endotracheal tube (ETT)
• (2) mechanical ventilation with spontaneous breathing modes which are CPAP, PIPAP and PSV
• (3) FOUR score equal to or more than 13,
• (4) RASS score from -1 to +4.

Exclusion Criteria: Patients with

• (1) respiratory asthma
• (2) chronic obstructive pulmonary disease
• (3) acute respiratory distress syndrome,
• Sniffin' Sticks-test score of smell less than 17

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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106 participants in 2 patient groups, including a placebo group

Peppermint group

Experimental group

Description:

This group will receive peppermint oil aroma

Treatment:

Other: Aromatherapy

Water group

Placebo Comparator group

Description:

This group will receive water as an aroma oil

Treatment:

Other: Placebo