Per-procedural Concentration of Direct Oral Anticoagulants (CORIDA)

Fondation Ophtalmologique Adolphe de Rothschild

Status

Completed

Conditions

Per-procedural Concentrations of Oral Anticoagulants

Treatments

Other: DOAC concentration measurement

Study type

Observational

Funder types

NETWORK

Identifiers

NCT02643992

AGR_2014-13

Details and patient eligibility

About

Background: Peri-procedural management of direct oral anticoagulants (DOAC) is challenging. The optimal duration of pre-procedural discontinuation that guarantees a minimal DOAC concentration ([DOAC]) at surgery is unknown. The usual 48-hour discontinuation might not be sufficient for all patients.

Objectives: To investigate the factors associated with per-procedural [DOAC]. To test the hypothesis that a 48-hour DOAC discontinuation is not sufficient to ensure a minimal perprocedural [DOAC], defined as [DOAC] < 30 ng/mL.

Methods: Patients treated with DOAC, and requiring any invasive procedure will be included in this multicentre, prospective, observational study. [DOAC], will be measured during invasive procedure.

Enrollment

270 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria