Perception of Blood Sugar Variations During Physical Activity in Healthy Subjects and Type 1 Diabetes Patients (GLYSPORT)

Université de Reims Champagne-Ardenne

Status: Unknown

Conditions: Type 1 Diabetes

Treatments: Other: Physical activity

Study type: Interventional

Funder types: Other

Identifiers

NCT05357534

2022-RIPH_002_GLYSPORT

Details and patient eligibility

About

Type 1 diabetes is an autoimmune disease with absence of insulin secretion. Blood sugar is a physiological variable that reflets for blood glucose concentration. Blood sugar level fluctuates, especially during physical activity.

Sports activity would increase insulin sensitivity, improve lifestyle and, by extension, promote glycemic balance. However, glycemic balance will be disturbed by physical activity with higher risk of hypoglycemia and hyperglycemia.

Moreover, hypoglycemia and hyperglycemia will impact body functions. Perceptions of blood sugar variations during physical exercise and their influences on sports performance have not been studied, whether in type 1 diabetes patients or healthy subjects.

Full description

The aim of the study is to evaluate the perception of blood sugar variations in healthy subjects and type 1 diabetes patients during physical activity

Enrollment: 30 estimated patients

Sex: Male

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Type 1 diabetics diagnosed more than 3 years ago and controlled (an HbA1c of less than 8%) for "type 1 diabetes" group
• without diabetes for "healkthy" group
• Male
• Aged 18 to 65
• Body Mass Index less than 30 kg/m2
• regular running (at least 30 minutes per week and at least one 10-km run per year for the previous 2 years)
• Agreeing to participate in the study

Exclusion criteria

• Physical injury
• beta blockers treatment

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

"Type 1 diabetes" group

Experimental group

Description:

"type 1 diabetes" group: patients with type 1 diabetes

Treatment:

Other: Physical activity

"healthy" group

Active Comparator group

Description:

"healthy" group : subjects without type 1 diabetes

Treatment:

Other: Physical activity