ClinicalTrials.Veeva

Menu

Perceptual Influences From Smoking Cannabis: an Experimental Study (PISCES)

U

University of Colorado Boulder (CU)

Status

Enrolling

Conditions

Cannabis Use
Stress

Treatments

Other: Water Temperature Variation - WW
Other: Water Temperature Variation - CW

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT06588582
1K01DA058152-01A1 (U.S. NIH Grant/Contract)
23-03-0215

Details and patient eligibility

About

The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognition, perception including the experience of temperature and pain, and heart rate.

We expect that participants will be in this research study for approximately one week. The total amount of time that participants will spend completing study tasks will be about 2.5 hours across two separate in-person visits.

Enrollment

166 estimated patients

Sex

All

Ages

21 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 21-65 years of age
  • Endorsement of at least some use of cannabis for coping purposes (>1 on CMMQ)
  • Regularly use flower cannabis products (i.e., ≥1x/week in the last 6 months)
  • Proficient in English language
  • At least occasional use of CBD+THC or CBD-dominant products (e.g., ≥1x/month)

Exclusion criteria

  • Diagnosis or use of medications for substance use or psychotic disorders
  • Report of other drug use (cocaine, opiates, methamphetamine) in the past 90 days or fail urine screen for any of these drugs
  • Females cannot be pregnant or trying to become pregnant or nursing mothers
  • Not able to provide informed consent

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

166 participants in 2 patient groups, including a placebo group

Cold Water
Experimental group
Treatment:
Other: Water Temperature Variation - CW
Warm Water
Placebo Comparator group
Treatment:
Other: Water Temperature Variation - WW

Trial contacts and locations

1

Loading...

Central trial contact

Carillon Skrzynski, PhD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems