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Objectives. To develop a new treatment for amblyopia using a perceptual learning approach.
Hypothesis to be tested. Our proposed experiments are designed to investigate whether practicing a grating detection task can improve vision in patients with amblyopia.
Design and subjects. A total of 36 patients with amblyopia will be randomized allocated into two intervention groups: Group 1, perceptual learning therapy. Group 2, occlusion therapy. A control group comprising of 18 subjects with normal vision will be recruited for comparison. A battery of tests will be used to assess a range of visual functions before and after the treatment intervention.
Study instruments. Grating acuity testing system
Interventions. We have established a clinical protocol for acuity training. On each trial, a properly oriented stimulus will be presented randomly at one of the four locations on a flat monitor screen. The visual task is to indicate the location of the stimulus. Participants will be required to undertake 20 one-hour sessions of training.
Main outcome measures. Resolution acuity, visual acuity, contrast sensitivity function
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54 participants in 3 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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