PERFECT Project - Part 1 - Study 2

University of Manitoba

Status: Completed

Conditions: Obesity Prevention; Diabetes Prevention

Treatments: Other: Pea protein; Other: Pea starch; Other: Control; Other: Pea fibre + pea starch + pea protein; Other: Pea fibre + pea starch; Other: Pea protein + pea starch

Study type: Interventional

Funder types: Other

Identifiers

NCT02366572

B2014:114-3

Details and patient eligibility

About

The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) post-prandial blood glucose, insulin and appetite for two hours, and 2) food intake two hours following consumption of pulse products.

We hypothesize that cereals containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake responses compared to non-pulse cereals.

Enrollment: 26 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
• BMI of 18.5-29.9 kg/m2

Exclusion criteria

• Restrained eaters
• Regularly skip breakfast
• Smokers
• Competitive sports or athletic training at a high intensity
• Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year.
• Those unable to walk for an hour continuously

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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26 participants in 6 patient groups, including a placebo group

Cereal control

Placebo Comparator group

Description:

100% Wheat Flour

Treatment:

Other: Control

Cereal with pea protein

Experimental group

Description:

Pea protein

Treatment:

Other: Pea protein

Cereal with pea starch

Experimental group

Description:

Pea starch

Treatment:

Other: Pea starch

Cereal w/ pea starch + pea fibre: 5g

Experimental group

Description:

Pea starch + pea fibre: 5g

Treatment:

Other: Pea fibre + pea starch

Cereal w/ pea protein + pea starch: 10g

Experimental group

Description:

Pea protein + pea starch: 10g

Treatment:

Other: Pea protein + pea starch

Cereal w/ pea protein + pea fibre + pea starch: 20g

Experimental group

Description:

Pea protein + pea fibre + pea starch: 20g

Treatment:

Other: Pea fibre + pea starch + pea protein