PERFECT Project - Part 2 - Study 2

University of Manitoba

Status: Completed

Conditions: Obesity Prevention; Diabetes Prevention

Treatments: Other: Pea protein + pea starch; Other: Pea Starch; Other: Pea protein; Other: Pea fibre + pea starch; Other: Control; Other: Pea fibre + pea starch + pea protein

Study type: Interventional

Funder types: Other

Identifiers

NCT02370927

B2014:114-4

Details and patient eligibility

About

The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. The investigators hypothesize that consumption of cereals containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. The investigators also hypothesize that consumption of cereals containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.

Enrollment: 30 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
• Body Mass Index of 18.5-29.9 kg/m2

Exclusion criteria

• Restrained eaters
• Regularly skip breakfast
• Smokers
• Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year
• Those who are active (organized activities or athletic training at a high intensity; ≥ 150 minutes per week of moderate to vigorous physical activity)
• Those unable to walk for an hour continuously

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

30 participants in 6 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

100% Wheat Flour

Treatment:

Other: Control

Cereal w/ pea protein

Experimental group

Description:

Pea protein

Treatment:

Other: Pea protein

Cereal w/ pea starch

Experimental group

Description:

Pea starch

Treatment:

Other: Pea Starch

Cereal w/ pea starch + pea fibre

Experimental group

Description:

Pea starch + pea fibre: 5g

Treatment:

Other: Pea fibre + pea starch

Cereal w/ pea protein + pea starch

Experimental group

Description:

Pea protein + pea starch: 10g

Treatment:

Other: Pea protein + pea starch

Cereal w/ pea protein + pea fibre + pea starch:

Experimental group

Description:

Pea protein + pea fibre + pea starch: 20g

Treatment:

Other: Pea fibre + pea starch + pea protein