Performance in Walking in Osteoarthritis Patients (EX-ART)

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Osteoarthritis

Treatments: Other: concentric work; Other: eccentric work

Study type: Interventional

Funder types: Other

Identifiers

NCT03167502

16-AOIP-03

Details and patient eligibility

About

Few data exist to date on the effect of eccentric muscle building in knee osteoarthritis. No studies have compared the effect of eccentric versus concentric reinforcement in knee osteoarthritis. Our study aims to show the effectiveness of an eccentric reinforcement. This is a randomized, interventional trial.

Full description

Few data exist to date on the effect of eccentric muscle building in knee osteoarthritis. No studies have compared the effect of eccentric versus concentric reinforcement in knee osteoarthritis. Our study aims to show the effectiveness of an eccentric reinforcement, the interest of a work supervised by a sports coach to maintain activity over time and to study the effect of this activity at the muscular level. The main objective is to study the effect of an eccentric muscle strengthening program on walking performance in osteoarthritis patients. The secondary objectives are to study: the effect of fatigue on walking, the relationship between fatigue and the level of physical activity, the effect of training on perceived fatigue and the effect of training on the function and at muscular level. This is a randomized, interventional trial. 40 subjects are planned. Inclusion criteria include: age 40-85 years, KL 2 and 3. The subjects are divided into two groups to perform either eccentric or concentric work. 2 sessions per week for 6 weeks. At baseline and at the end of the study a clinical evaluation and MRI will be carried out for evaluation of the criteria of judgment

Enrollment: 40 patients

Sex: All

Ages: 40 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Autonomous subjects aged 40 to 85
• Subjects meeting ACR criteria for gonarthrosis
• Subjects with a score of Kellgren and Lawrence at least one knee greater than or equal to 2
• Signature of consent form
• Subjects affiliated to social security

Exclusion criteria

Subject with a Kellgren and Lawrence stadium at 4 for at least one of his two knees

• Subjects with symptomatic femoro-patellar arthrosis
• Subject with a pathology that makes walking testing impossible.
• Non-autonomous subjects, with a pathology impairing walking
• Subjects with symptomatic osteoarthritis of the hip and / or with a hip or knee prosthesis
• Subject incapable of signing consent and unable to understand information leaflet.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

concentric work

Active Comparator group

Description:

patient suffering from knee osteoarthritis will follow a concentric work. This training is 2 sessions per week for 6 weeks

Treatment:

Other: concentric work

eccentric work

Experimental group

Description:

patient suffering from knee osteoarthritis will follow an eccentric work. This training is 2 sessions per week for 6 weeks

Treatment:

Other: eccentric work