Performance of CAST (Cellular Antigen Stimulation Test) in Patients With Wasp Venom Allergy: Evaluation of Neutralizing IgG Subclasses

University of Zurich (UZH)

Status: Withdrawn

Conditions: Wasp Venom Allergic Patients

Treatments: Other: Taking blood samples

Study type: Observational

Funder types: Other

Identifiers

NCT00794287

ZU-AgNT-004

Details and patient eligibility

About

To determine which subclass of IgG in the serum of patients undergoing SIT against wasp venom is able to neutralize the allergen, and therefore to prevent a positive CAST

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• male and female patient with allergy to wasp venom grade III and IV according to H.L. Müller
• 18-75 years
• planned SIT against wasp venom or finished 5 years SIT against wsp venom (10/10)

Exclusion criteria

• oral corticosteroids
• chromogycin
• ketotifen
• immunosuppressive drugs within the last 2 years

Trial design

0 participants in 2 patient groups

1

Description:

Hymenoptera allergic patients before allergen specific immunotherapy

Treatment:

Other: Taking blood samples

2

Description:

Hymenoptera allergic patients after allergen specific immunotherapy

Treatment:

Other: Taking blood samples