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Performance of Mid-Upper Arm Circumference for Detection of Severe Acute Malnutrition in Indonesian Under-Fives

U

University of Indonesia (UI)

Status

Completed

Conditions

Severe Acute Malnutrition

Treatments

Diagnostic Test: Mid-upper arm circumference

Study type

Observational

Funder types

Other

Identifiers

NCT06545240
19-12-1452

Details and patient eligibility

About

WHO recommends 11.5 cm as a cut-off point of Mid-Upper Arm Circumference (MUAC) to detect and/or diagnose severe acute malnutrition (SAM) in under-five. MUAC is practical and useful, especially in area with limited facilities which has no standardized scale and infantometer. However, several studies showed that this cut-off need to be evaluated as it has modest detection rate for SAM. This study aims to evaluate diagnostic value of MUAC with 11.5 cm cut-off compared to WHZ as gold standard to identify SAM. The sensitivity, specificity, positive and negative predictive value of MUAC with 11.5 cm as a standard cut-off will be evaluated.

This study also aim to find new cut-off value that may offer better diagnostic performance. The main research questions were:

What is the diagnostic accuracy of Mid-Upper Arm Circumference (MUAC) compared to the Weight for Height Z Score (WHZ) in identifying SAM in children, and what is the optimal MUAC cut-off value for enhanced diagnostic performance?

Enrollment

421 patients

Sex

All

Ages

6 to 59 months old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • under-fives that 6-59 months-old

Exclusion criteria

  • ascites
  • edema
  • hydrocephalus
  • tumor or oncologic diseases
  • organomegaly
  • uncooperative during measurement

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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