Performance of New Diagnostic Methods in Older Adults With Pneumonia (PNEUMO)

The Ohio State University

Status: Enrolling

Conditions: Pneumonia

Study type: Observational

Funder types: Other

Identifiers

NCT06092008

2022H0136

Details and patient eligibility

About

Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.

Enrollment: 250 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

- Adults aged 65 and older presenting to the ED with suspected pneumonia defined as (1) either a physician order for CXR OR CT OR a chief complaint consistent with dyspnea; AND (2) physician suspicion of pneumonia prior to ED testing (score of 2-5 on Likert scale)

Exclusion criteria

• inability to obtain consent from the patient or an LAR
• active cancer
• organ transplant
• immunosuppression
• trauma activation
• suicidal ideation
• incarceration
• antibiotics in the last 14 days
• a separate episode of lower respiratory illness in the last 30 days