Performance of Six Equations for Estimating Resting Energy Expenditure in Patients With Type 2 Diabetes

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis

Status: Completed

Conditions: Diabetes Mellitus, Type 2

Treatments: Other: Observational

Study type: Observational

Funder types: Other

Identifiers

NCT04484883

6/2020

Details and patient eligibility

About

The present study evaluated the statistical and clinical performance of the six common equations in subjects with type 2 diabetes adopting indirect calorimetry as reference standard

Full description

All consecutive subjects with type 2 diabetes referred from June 2012 to December 2019 were eligible. They were excluded if data on ongoing therapy, anthropometric or laboratory parameters, or measured REE was not available or if presenting with conditions known to affect indirect calorimetry.

Enrollment: 250 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with type 2 diabetes
• Available resting energy expenditure assessed by indirect calorimetry

Exclusion criteria

• data on ongoing therapy (e.g. lifestyle measures with or without approved drugs), anthropometric or laboratory parameters (including white blood count, estimated glomerular filtration rate, TSH), or REE assessed by the means of indirect calorimetry could not be retrieved
• presenting with conditions known to affect indirect calorimetry (e.g. patients with strenuous exercise on the day before, asymptomatic patients with severe chronic kidney disease (eGFR < 30 ml/min/ 1.73 m2), increased white blood count, or subnormal TSH)