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Perfusion and Dual Energy Computer Tomography in Hepatocellular Carcinoma (PERCAHEC)

A

Assistance Publique - Hôpitaux de Paris

Status

Unknown

Conditions

Hepatocellular Carcinoma

Treatments

Radiation: perfusion Computed Tomography

Study type

Interventional

Funder types

Other

Identifiers

NCT03754192
APHP180011

Details and patient eligibility

About

The aim of this study is to evaluate the hepatic perfusion computer tomography and dual energy computer tomography in the assessment of tumor characterization of Hepatocellular carcinoma in patients with resectable Hepatocellular carcinoma by comparing the quantitative parameters computer tomography obtained with the pathological data of the surgical specimens.

Full description

Dual-energy computer tomography and perfusion computer tomography (General Electric revolution Hight definition Gemstone™ Spectral Imaging) will be performed in all patients. Iodine concentration and quantitative perfusion parameters of the Hepatocellular carcinoma and surrounding liver parenchyma data will be compared with the pathological results.

Enrollment

50 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • A diagnosis of Hepatocellular carcinoma made according to the guidelines of the American Association for the study of the Liver
  • Affiliation to a national health insurance
  • An indication for hepatic resection during the decision-making stage
  • A request for a pre-operative Computer Tomography in our radiology unit
  • An affiliation to a social security
  • Informed consent given by the patient

Exclusion criteria

  • Previous treatments of Hepatocellular carcinoma (medicated or surgical)
  • Patient under tutorship or curatorship
  • Pregnant or lactating woman

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

50 participants in 1 patient group

perfusion computed tomography
Other group
Description:
Will be realsed before liver surgery
Treatment:
Radiation: perfusion Computed Tomography

Trial contacts and locations

1

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Central trial contact

DA-MOTA-FERREIRA Jean-Manuel, Radiologic; LEWIN MAITE, MD, Phd

Data sourced from clinicaltrials.gov

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