Perfusion CT Imaging in Lung Cancer With SBRT

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University Health Network, Toronto

Status

Completed

Conditions

Lung Cancer

Treatments

Device: Perfusion CT Imaging

Study type

Interventional

Funder types

Other

Identifiers

NCT02755454
12-5386-CE

Details and patient eligibility

About

The goal of this study is to determine specific perfusion patterns for radiation induced lung changes and residual/recurrent lung malignancies in patients treated with stereotactic body radiotherapy SBRT and thus improve to distinguish radiation changes from residual/recurrent lung cancers. Currently CT is often unable to make a clear differentiation between benign and malignant changes in the lung after SBRT treatment necessitating additional wait time to perform follow up CTs or biopsies. Optimal treatment may be delayed. The investigators want to apply a CT perfusion sequence in addition to the routine follow up CTs with the goal to obtain perfusion values of post treatment lung changes and lung tumours. The investigators' hypothesis is that CT perfusion values will help differentiate benign post radiation changes from residual/recurrent tumour in the lung with higher confidence and may help avoid unnecessary delays in cancer treatment.

Enrollment

9 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Gender: male or female
  • CT ordered for baseline and follow up in patients with lung cancer and lung metastases treated with
  • Patient will sign a consent form prior to study entry
  • Lung cancer and lung metastases are biopsy proven

Exclusion criteria

  • Patients who are unable to give valid informed consent
  • Patients who are unwilling or unable to undergo a CT exam, including subjects with contra-indications to CT exams or intravenous contrast material administration.

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

9 participants in 1 patient group

open label
Other group
Description:
Perfusion CT Imaging
Treatment:
Device: Perfusion CT Imaging

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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