Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section

Zagazig University

Status: Enrolling

Conditions: Post Spinal Hypotension

Treatments: Other: perfusion index in all parturient recruited for the study

Study type: Observational

Funder types: Other

Identifiers

NCT05587153

9293/2-2-2022

Details and patient eligibility

About

Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section

Full description

Hypotension following spinal anaesthesia may cause maternal dizziness, nausea, vomiting and fetal acidosis, administration of prophylactic vasopressor agents in pregnant women may cause undesirable effects on the mother and fetus. Perfusion index is the ratio of a pulsatile to a non-pulsatile fraction of blood volume. The increase of the pulsatile fraction manifested during vasodilatation corresponds to a higher PI. So, the patients with a higher PI have a higher risk for post-spinal hypotension. Elevated sympathetic activity before neuraxial anaesthesia was associated with a higher risk for post-spinal hypotension. The significant variability in haemodynamic after the positional change indicates higher sympathetic activity. The high the rise in autonomic activity, the higher the risk for post-spinal hypotension

AIM OF THE WORK:

Prediction of hypotension after spinal anaesthesia in caesarean section either by perfusion index and positional haemodynamic changes

Grouping:

All the recruited patients will be assessed by perfusion index. and by positional haemodynamic changes

Enrollment: 80 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

• Parturient acceptance.
• American Society of Anesthesiologists (ASA) II
• arturient with be gestational age >36 weeks and <41 weeks.
• Body mass index (BMI) ≤35kg/m2
• elective caesarean section delivery

Exclusion criteria

• preeclampsia
• eclampsia,
• gestational diabetes
• Contraindication to regional anaesthesia as allergy, coagulation abnormalities or infection in site of injection.

Trial design

80 participants in 1 patient group

Observational study in parturient who will be recruited for the study

Description:

this study will include the eligible parturient who will be assessed by perfusion index and by positional hemodynamic changes.

Treatment:

Other: perfusion index in all parturient recruited for the study