Peri-operative Foot CT Perfusion in CLI Patients (POP-CLI)

Fudan University

Status: Active, not recruiting

Conditions: Critical Limb Ischemia

Treatments: Diagnostic Test: computed tomographic perfusion

Study type: Observational

Funder types: Other

Identifiers

NCT05575778

2022KW

Details and patient eligibility

About

To investigate the clinical value of quantitative analysis of peri-operative foot supply through CT perfusion in patients with critical limb ischemia

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 to 80 years old;
• CLI patients with Fontaine grade III-IV or Rutherford grade 4-6 and underwent a successful revascularization;
• Patients completed both pre- and post-operative CTP workups;
• Patients signed the informed consent form and be able to complete the clinical follow-up for 12 months.

Exclusion criteria

• Patients has participated in other clinical studies;
• Patients with Heart failure (NYHA III/IV)/right to left shunt heart disease/severe aortic and mitral insufficiency/acute coronary syndrome/malignant arrhythmia/severe pulmonary hypertension (pulmonary artery pressure at least 90 mmHg)/moderate to severe renal insufficiency (creatinine clearance rate<60 ml/min)
• Any allergic constitution;
• Pregnancy and childbirth;
• Life expectancy<12 months.