Pericapsular Nerve Group Block Chemical Neurolysis in Advanced Hip Osteoarthritis (PENG)

Poznan University of Medical Sciences (PUMS)

Status and phase: Completed; Phase 4

Conditions: Osteoarthritis, Hip; Osteoarthritis

Treatments: Drug: 0.9%sodium chloride; Drug: 95% ethanol

Study type: Interventional

Funder types: Other

Identifiers

NCT06087588

5/2023

Details and patient eligibility

About

PENG neurolysis in advanced osteoarthritis of the hip joint.

Full description

The study aims to assess the safety and effectiveness of regional pain treatment methods and their impact on the quality of life of patients with advanced osteoarthritis of the hip joint.

Enrollment: 100 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of the Pain Treatment Clinic of the Transfiguration of Jesus Clinical Hospital of the Medical University of Poznań will be qualified for the study
• patients with coxarthrosis or gonarthrosis who failed to achieve satisfactory pain control (NRS>3) despite the use of NSAIDs, Paracetamol, and co-analgetics
• Age of patients: from 18 to 110 years of age.
• Caucasian patients can give informed, complete, written consent.

Exclusion criteria

• suspected or diagnosed opioid dependence syndrome
• active cancer
• dementia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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100 participants in 2 patient groups

sham PENG block

Active Comparator group

Description:

PENG block - 20ml 0,9% normal saline

Treatment:

Drug: 0.9%sodium chloride

PENG neurolysis

Active Comparator group

Description:

PENG neurolysis with 5ml 95% ethanol

Treatment:

Drug: 95% ethanol