Pericapsular Nerve Group (PENG) Block Combined With Periarticular Multimodal Drug Injection (PMDI) Versus Isolated PMDI for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial

Yonsei University

Status: Unknown

Conditions: Total Hip Arthroplasty, Postoperative Pain

Treatments: Procedure: Pericapsular nerve group(PENG) block combined with periarticular multimodal drug injection (PMDI); Procedure: isolated periarticular multimodal drug injection (PMDI)

Study type: Interventional

Funder types: Other

Identifiers

NCT05320913

4-2021-1482

Details and patient eligibility

About

Adequate pain control after total hip arthroplasty is crucial for early ambulation and patient satisfaction. However, there is no consensus about optimal pain control after post operation. In general, the periarticular multimodal durg injection block has been done for pain control in primary total hip arthroplasty. The pericapsular nerve group (PENG) block has been recently introduced a new technique for blockade of the articular branches of the femoral, obturator and accessory obturator nerves. PENG block is possible to provide sufficient analgesia and preserve lower limb muscle strength. The investigators will compare PENG and PMDI block with isolated PMDI block in patients undergoing total hip arthroplasty.

Enrollment: 58 estimated patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients aged 19 years old or older, with American Society of Anesthesiologists Physical Status 1-3, and scheduled for elective unilateral total hip arthroplasty

Exclusion criteria

1. Allergy or intolerance to any of the drugs used in the study
2. Hepatic or renal insufficiency
3. Opioid dependency
4. Coagulopathy
5. Pre-existing neurologic or anatomic deficits in the lower extremities
6. Severe psychiatric illness

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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58 participants in 2 patient groups

Pericapsular nerve group(PENG) block combined with periarticular multimodal drug injection (PMDI)

Experimental group

Description:

Participants receiving pericapsular nerve group(PENG) block combined with periarticular multimodal drug injection (PMDI)

Treatment:

Procedure: Pericapsular nerve group(PENG) block combined with periarticular multimodal drug injection (PMDI)

isolated periarticular multimodal drug injection (PMDI)

Active Comparator group

Description:

Arm Description: Participants receiving isolated periarticular multimodal drug injection (PMDI)

Treatment:

Procedure: isolated periarticular multimodal drug injection (PMDI)