Perifollicular Doppler in Natural Cycle In Vitro Fertilization

Ovo Clinic

Status: Completed

Conditions: Infertility

Treatments: Procedure: Doppler ultrasound

Study type: Observational

Funder types: Industry

Identifiers

NCT01668212

OVO-11-01

Details and patient eligibility

About

Perifollicular Doppler could reflect the quality of the follicle's vascularization and, consequently, the one of the oocyte that ensues from it. Perifollicuar Doppler is the analysis, in ultrasound, of the blood flow in vessels surrounding the follicle.

The goal of this study is to evaluate if there is a link, in natural cycle In Vitro Fertilization, between the quality of the vascularization and the one of the oocyte, the embryo and the pregnancy.

Enrollment: 160 patients

Sex: Female

Ages: 18 to 38 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with a natural In Vitro Fertilization cycle.
• Patient under 38 years old
• Body mass indice under 35
• Ovulatory cycles between 20-35 days

Exclusion criteria

• Patient with a stimulation In Vitro Fertilization cycle
• Patient with a naturalIn Vitro Fertilization cycle with egg donor
• Patient with a natural In Vitro Fertilization cycle with freezing embryo
• Smoking patient
• Diabetic patient
• Patient with treatment of antihypertensive drug, anticoagulant, antiplatelet, vasodilator
• Body mass indice over 35
• Patient over 38 years old
• Patient without ovulation or cycle over 35 days
• Percutaneous Epididymal Sperm Aspiration (PESA), Testicular Sperm Extraction (TESE) or micro TESE

Trial design

160 participants in 1 patient group

natural In Vitro Fertilization cycle

Description:

Patient doing following natural In Vitro fertilization cycle

Treatment:

Procedure: Doppler ultrasound