Perinatal Thymic DYsregulation: Characterization of Perinatal Mood Episodes (DYP)

Centre Hospitalier Charles Perrens, Bordeaux

Status: Enrolling

Conditions: Perinatal Mental Health

Treatments: Other: self-questionnaires

Study type: Interventional

Funder types: Other

Identifiers

NCT07008183

ID-RCB (Other Identifier)

2024-A02708-39

Details and patient eligibility

About

The perinatal period is recognized as a time of heightened psychological vulnerability. This research aims to improve the diagnosis and therapeutic management of mood episodes occurring during this time. It is integrated into routine clinical care and seeks to standardize the evaluation of criteria used to characterize mood episodes, while also exploring relevant contextual factors.

Traditionally, clinical attention has focused on postnatal depression; however, increasing evidence highlights the presence of hypomanic symptoms-such as distractibility, reduced need for sleep, tachypsychia, and irritability-during the postpartum period. These symptoms may coexist with depressive features, resulting in complex clinical presentations that are often difficult to recognize and manage. Consequently, many cases go undiagnosed and untreated.

Current research has largely concentrated on depressive episodes (perinatal depression), with less emphasis on manic, hypomanic, or mixed episodes indicative of bipolar disorder. A systematic evaluation of hypomanic symptoms occurring alongside depressive symptoms in the postpartum period could refine clinical diagnosis and support more targeted and effective therapeutic interventions.

Enrollment: 200 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women over 18 years old
• Pregnant or having given birth less than a year ago
• First psychiatric consultation for the pregnancy concerned.
• Good command of the French language.
• Participant affiliated to the social security system
• Participant who has given her consent to take part in the study.

Exclusion criteria

• Women who gave birth more than a year ago.
• Participant under psychiatric care
• Participant under court protection

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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200 participants in 1 patient group

Usual care

Experimental group

Description:

The study aims to systematize the evaluation of the various criteria used to characterize mood episodes, and to explore contextual elements.

Treatment:

Other: self-questionnaires