Periodization and Parkinson's Disease

University of Miami

Status: Enrolling

Conditions: Activity, Motor

Treatments: Behavioral: Periodized Resistance Training; Behavioral: Power Resistance Training

Study type: Interventional

Funder types: Other

Identifiers

NCT07141849

20250800

Details and patient eligibility

About

This study will compare the effects of high-speed power resistance training to periodized training, which includes cycle of hypertrophy, strength and power, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.

Enrollment: 60 estimated patients

Sex: All

Ages: 50 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parkinson's Disease Hoehn & Yahr Stages 1-3
• Able to walk 50m unassisted
• Able to understand and communicate in English

Exclusion criteria

• Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program
• Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness
• Unresolved injury or surgery to the upper or lower limbs that prevents weight training.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Power Resistance Training

Active Comparator group

Description:

Participants will receive high-speed power resistance training, twice per week for at least 24 sessions for up to 12 weeks.

Treatment:

Behavioral: Power Resistance Training

Periodized Resistance Training

Experimental group

Description:

Participants will receive periodized resistance training twice per week for at least 24 weeks.

Treatment:

Behavioral: Periodized Resistance Training