Periodization of Exercise Training in Patients With Coronary Heart Disease. (PERIOD)

University of Montreal

Status: Completed

Conditions: Healthy Control; Coronary Heart Disease

Treatments: Other: Exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT03443193

MontrealHI 2015-1895

Details and patient eligibility

About

The research project includes two components that assess exercise physiology parameters, cerebrovascular reserve, cognitive functions and cardiac function in coronary heart disease patients at rest, during an acute exercise, and after two different periodized training programs.

Enrollment: 70 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria for patients with coronary heart disease:

• Major
• Adequate physical and mental capacities
• Autonomy in daily activities
• Documented coronary artery disease
• Stable or recent coronary artery disease

Exclusion Criteria for patients with coronary heart disease:

• Inability to complete the consent form
• Acute coronary syndrome < 3 months
• Heart failure
• Ejection fraction of the left ventricle <40%
• Coronary artery disease non revascularisable including left main coronary stenosis
• Waiting for a bridging of the coronary artery
• Chronic atrial fibrillation
• Malignant arrhythmias during exercise
• Restriction to non cardiopulmonary exercise
• Severe intolerance to exercise

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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70 participants in 2 patient groups

Linear training

Experimental group

Description:

Linear training consists to a progressive improvement of the training load during the 3 month-program.

Treatment:

Other: Exercise training

Non-linear training

Experimental group

Description:

Non-linear training consists to an undulating progressive improvement of the training load during the 3 month-program.

Treatment:

Other: Exercise training