Periodontal Disease and Preterm Birth
Status
Conditions
Details and patient eligibility
About
To determine the relationship between periodontal disease and upper genital tract inflammation in pregnancy. To determine whether certain fluid levels in the oral cavity and the vagina are associated with preterm birth or low-birth weight.
Full description
Patients will be enrolled in the study at their first prenatal visit after the details of the study have been discussed. Potential subjects will be presented with a questionnaire to determine eligibility for the study. The patient will be scheduled for an exam between 18-24 weeks at which time they will undergo a periodontal assessment, to determine the presence or absence of periodontal disease, a sampling of gingival crevicular fluid (GCF) and a vaginal swab collection. Periodontal disease will be determined by measuring the depth of gingival sulci, amount of periodontal attachment loss, and prevalence of gingival bleeding at six sites for each tooth present.
Sex
Ages
Volunteers
Inclusion criteria
- Between the ages of 15-35
- Singleton gestation
Exclusion criteria
- Diabetes prior to pregnancy
- Require antibiotic prophylaxis prior to dental treatment
- Require steroids during pregnancy
Trial design
0 participants in 1 patient group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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