Periodontal Status and Pregnancy or Delivery Complications in Type 1 Diabetes Mellitus Pregnant Women

University of Ljubljana

Status: Completed

Conditions: Diabetes Mellitus, Type 1; Periodontitis; Pregnancy Complications; Pregnancy in Diabetic; Periodontal Diseases; Delivery Complication

Treatments: Other: Periodontal disease; Other: Pregnancy and/or delivery complications

Study type: Observational

Funder types: Other

Identifiers

NCT06002997

Pregnancy, DM, Periodontitis

Details and patient eligibility

About

The results of contemporary studies suggest an association between inflammatory periodontal disease and pregnancy and delivery complications. The aim of this study was to assess the association between periodontal disease, clinical periodontal parameters and pregnancy or delivery complications in type 1 diabetes mellitus and non-diabetic pregnant women.

Full description

The results of contemporary studies suggest an association between inflammatory periodontal disease and pregnancy and delivery complications. The aim of this study was to assess the association between periodontal disease, clinical periodontal parameters and pregnancy or delivery complications in type 1 diabetes mellitus and non-diabetic pregnant women. Methods: 15 type 1 diabetes mellitus and 15 non-diabetic primiparous women were enrolled in the prospective "case-control" study. Investigators compared periodontal status, levels of glycosylated haemoglobin (HbA1c), high sensitivity C-Reactive Protein (hs-CRP), gestational week of birth, birth weight of a newborn and pregnancy or delivery complications (C-section, pre-eclampsia) between the groups.

Enrollment: 30 patients

Sex: Female

Ages: Under 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy Pregnant Women
• Pregnant Women with Diabetes Mellitus type 1
• Healthy Pregnant Women with signs of Periodontal Disease
• Pregnant Women with Diabetes Mellitus type 1 and signs of Periodontal disease

Exclusion criteria

• Smokers
• Former smokers who had stopped smoking less than five years before participation
• Pregnant women with other systemic diseases

Trial design

30 participants in 2 patient groups

Control Group

Description:

Healthy pregnant women

Treatment:

Other: Periodontal disease

Other: Pregnancy and/or delivery complications

Case Group

Description:

Pregnant women with Diabetes Mellitus Type 1

Treatment:

Other: Periodontal disease

Other: Pregnancy and/or delivery complications