Periodontal Therapy in Coronary Artery Patients (PerioCardio)

Federal University of Rio Grande do Sul

Status: Completed

Conditions: Coronary Artery Disease; Atheroma; Cardiovascular Diseases

Treatments: Device: Subgingival scaling and root planing; Device: Oral prophylaxis

Study type: Interventional

Funder types: Other

Identifiers

NCT01609725

HCPA110146

Details and patient eligibility

About

Gingival inflammation has been associated with cardiovascular diseases, including heart attack and stroke, because of elevation of blood risk markers such as cholesterol, glucose and C reactive protein. The treatment of gingival diseases decreases the concentration of these risk factors in the blood of cardiovascular patients.

Enrollment: 93 patients

Sex: All

Ages: 35 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 35 years and older
• coronary artery disease
• more than 10 teeth
• chronic periodontitis defined as 2 non-adjacent teeth with probing depth 5+mm and periodontal attachment loss 4+mm

Exclusion criteria

• use of antibiotics in the last 6 months
• periodontal therapy in the last 12 months

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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93 participants in 2 patient groups

Comprehensive treatment

Experimental group

Description:

Test treatment group

Treatment:

Device: Subgingival scaling and root planing

Community treatment

Other group

Description:

Control treatment group

Treatment:

Device: Oral prophylaxis