Perioperative Analgesia After Knee Arthroplasty

Landeskrankenhaus Feldbach

Status and phase: Unknown; Phase 4

Conditions: Knee Arthroplasty

Treatments: Procedure: Intraarticular and periarticular ropivacaine; Procedure: Continuous femoral nerve block + periarticular infiltration

Study type: Interventional

Funder types: Other

Identifiers

NCT01225484

21-315 ex 09/10

Details and patient eligibility

About

The purpose of this study is to compare two accepted methods of pain control in knee arthroplasty surgery.The first method combines the periarticular injection of ropivacaine with continuous blockade of the femoral nerve.The second method uses periarticular infiltration of ropivacaine in combination with an bolus of ropivacaine into an intraarticular catheter placed intraoperatively followed by a continuous intraarticular infusion of ropivacaine. All patient will also receive a sustained-release oral opioid and oral rescue opioids determined by pain severity using the Visual Analog Scale (VAS)

Enrollment: 123 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective primary knee arthroplasty
• ASA I,II,&III patients
• Spinal Anaesthesia

Exclusion criteria

• Patients refusing consent
• Contraindications to regional anaesthesia
• Preexisting neurological disease
• Alcohol or drug abuse
• Inability to use the outcome assessment tools
• Wheel chair or walker dependent
• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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123 participants in 2 patient groups

CFNB, periarticular infiltration

Active Comparator group

Treatment:

Procedure: Continuous femoral nerve block + periarticular infiltration

Intraarticular catheter, periarticular infiltration

Active Comparator group

Treatment:

Procedure: Continuous femoral nerve block + periarticular infiltration

Procedure: Intraarticular and periarticular ropivacaine