Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury

Chinese PLA General Hospital (301 Hospital)

Status: Completed

Conditions: Postoperative Acute Kidney Injury

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06462755

PLAGH-AOC-R01

Details and patient eligibility

About

To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population.

The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation.

Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.

Enrollment: 57,089 patients

Sex: All

Ages: 65 to 120 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• elderly patients (aged ≥ 65 years) undergoing non-cardiac surgeries

Exclusion criteria

• (1) Patients who underwent endoscopic or transplant procedures;
• (2) Patients who underwent surgeries lasting longer than 10 hours;
• (3) Patients who had severe preoperative kidney dysfunction, defined as preoperative sCr levels ≥ 353.6 μmol/L, or a baseline estimated Glomerular Filtration Rate (eGFR) < 15 ml/min per 1.73 m2;
• (4) Patients without sCr values at baseline or during follow-up to detect PO-AKI occurrences.

Trial design

57,089 participants in 1 patient group

elderly patients (aged ≥ 65 years)

Description:

elderly patients undergo surgeries

Treatment:

Other: No intervention