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Perioperative Evaluation of Immuno-inflammatory Parameters

U

Université Catholique de Louvain

Status

Terminated

Conditions

Combined Inflammatory and Immunologic Defect

Study type

Observational

Funder types

Other

Identifiers

NCT01454856
2011/30MAI/218

Details and patient eligibility

About

This study consists of evaluations, using blood tests, various immune, inflammatory and coagulation parameters in the perioperative settings (different substudies), without changing anything to what is expected.

This will allow us to clarify the possible impact of surgery and analgesia on perioperative activation of these pathways.

Full description

A significant number of published data can be concluded that surgery and anesthetic and analgesic techniques have an impact on immunity and inflammation.

However, none of these studies have been performed with modern techniques, much more reliable evaluation of immune activity, such as the assessment of monocytic degranulation by flow cytometry.

It is therefore important to document immune activity using these new techniques, our patients, perioperative. This will be analyzed, so observational, the potential impact of different therapeutic interventions the patient receives.

This study consists of evaluations, using blood tests, various immune, inflammatory and coagulation parameters in the perioperative settings (different substudies), without changing anything to what is expected.

This will allow us to clarify the possible impact of surgery and analgesia on perioperative activation of these pathways.

Enrollment

20 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Surgical patients (and controls)

Exclusion criteria

  • Immune disorders

Trial design

20 participants in 4 patient groups

Surgical cancer patients
Description:
No modification of the treatment
Non-surgical cancer patients
Description:
No modification of the treatment
Surgical non-cancer patients
Description:
No modification of the treatment
Non-surgical non-cancer patients
Description:
No modification of the treatment

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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